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The second-quarter edition of the 2024 MCGI Newsletter is now available! 📫 Explore our latest video resources, read the 2024 MCGI Forum recap, catch up on the newest updates from the MCGI team, and download our variant terminology resource. The Jackson Laboratory #QuarterlyMCGIUpdate
#Postdoc job of the week: Join the Rosenthal lab to research immune control of cardiac regeneration, identify biomarkers of aging, explore the inflammatory-fibrosis axis in ischemic heart failure, and study cellular senescence: https://bit.ly/3Uhx7lm #postdocs #postdocjobs
📗 New in PLOS Pathogens, "Systems genetics uncover new loci containing functional gene candidates in Mycobacterium tuberculosis-infected Diversity Outbred mice" with Daniel Gatti, Anna Tyler, Matt Mahoney & Gary Churchill: #jaxresearch
Is hereditary genetic testing is right for you? This 2-minute video, featuring The Maine Cancer Genomics Initiative (MCGI), helps explain how understanding genetic risk for cancer can help you and your family make better data-informed health choices:
Join us in Hamburg, Germany! JAX is excited to sponsor an Innovation Showcase at #ISSCR2024 on July 12 at 12 p.m., CEST, in Hall, 3 Entrance Level. JAX Professor Bill Skarnes will talk about our high-efficiency precision genome editing platform and how it is being utilized for large-scale engineering projects in #iPSCs. We are also thrilled to have Chan Zuckerberg Biohub Network (San Francisco) Scientist Camille Januel, PhD, join us to discuss her approach to iPSC organelle tagging using #CRISPR to study the effects of various disease-associated mutations at the cellular level. Don’t miss out on this opportunity to learn and connect with leading experts! Learn more about JAX's iPSC catalog here: https://bit.ly/3zvjoiG
JAX's Jason Bubier and colleagues have published research in Microbiome, from BMC. It shows that sodium valerate supplementation, with its ability to reduce binge drinking and anxiety-like behaviors in mice, offers a promising new avenue for treating alcohol use disorders. This underscores the critical role of the gut #microbiome in #addiction and highlighting the therapeutic potential of targeting the gut-brain axis:
📙 New in PLOS Computational Biology, "Common data models to streamline metabolomics processing and annotation, and implementation in a Python pipeline" with Joshua Mitchell, Yuanye Chi, Maheshwor Thapa & Shuzhao Li: #jaxresearch
JAX Center for Addiction Biology researchers Elissa J. Chesler, PhD, and Jason Bubier were recently interviewed by WABI TV 5. In this segment they discuss how using multiple mouse strains, they have seen trends similar to humans when it comes to susceptibility of #addiction and overdose, and how the likelihood of developing substance use disorder is not only biological, but that environment also plays a factor:
