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Gene linkage, codominance, incomplete dominance, alternation of generations explained1 Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction. Codominance is a relationship between two versions of a gene. Individuals receive one version of a gene, called an allele, from each parent. If the alleles are different, the dominant allele usually will be expressed, while the effect of the other allele, called recessive, is masked. The phenomenon in which two true-breeding parents crossed to produce an intermediate offspring (also known as heterozygous) is called incomplete dominance. ... In incomplete dominance, the variants (alleles) are not expressed as dominant or recessive; rather, the dominant allele is expressed in a reduced ratio. Youtube video: https://lnkd.in/dY2M79Kw #nikolaysgeneticslessons

🧬Fuchs' Dystrophy isn't just a random occurrence – it's often a part of your genetic heritage, passed down from generation to generation. This eye condition stems from a mutation in a gene crucial for producing a vital protein named collagen. But why is collagen important? It plays a key role in the health and functioning of the endothelium, the innermost layer of the cornea. The endothelium acts as a barrier and pump, keeping the cornea clear for optimal vision. When this genetic mutation occurs, the endothelium doesn’t work as it should, leading to the symptoms we associate with Fuchs' Dystrophy. #cornealdystrophy #eyecondition #eyeproblems #eyecare #eyeprotection #eyewellness #eyesight #visionproblems #visioncare #eyedisease #eyetreatment

'In this review, we provide an overview of the known mechanisms that confer mutational robustness and the role of mutational robustness in preserving phenotypic stability in the face of standing genetic variation or de novo mutations.' https://lnkd.in/dDtD96qC

Gene linkage, codominance, incomplete dominance, alternation of generations explained1 Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction. Codominance is a relationship between two versions of a gene. Individuals receive one version of a gene, called an allele, from each parent. If the alleles are different, the dominant allele usually will be expressed, while the effect of the other allele, called recessive, is masked. The phenomenon in which two true-breeding parents crossed to produce an intermediate offspring \(also known as heterozygous\) is called incomplete dominance. ... In incomplete dominance, the variants \(alleles\) are not expressed as dominant or recessive; rather, the dominant allele is expressed in a reduced ratio. Youtube video: https://lnkd.in/dzYV3kCf \#nikolays_genetics_lessons

Unusual genetic disorder inheritance explained Key terms Pedigree Chart that shows the presence or absence of a trait within a family across generations Genotype The genetic makeup of an organism (ex: TT) Phenotype The physical characteristics of an organism (ex: tall) Dominant allele Allele that is phenotypically expressed over another allele Recessive allele Allele that is only expressed in absence of a dominant allele Autosomal trait Trait that is located on an autosome (non-sex chromosome) Sex-linked trait Trait that is located on one of the two sex chromosomes Homozygous Having two identical alleles for a particular gene Heterozygous Having two different alleles for a particular gene Youtube video: https://lnkd.in/dDXVFzk5 #nikolaysgeneticslessons

Hello Connection I have written a article on CHROMOSOMAL ABNORMALITIES,]A chromosomal abnormality, chromosomal anomaly, chromosomal aberration, chromosomal mutation, or chromosomal disorder, is a missing, extra, or irregular portion of chromosomal DNA.These can occur in the form of numerical abnormalities, where there is an atypical number of chromosomes, or as structural abnormalities, where one or more individual chromosomes are altered. Chromosome mutation was formerly used in a strict sense to mean a change in a chromosomal segment, involving more than one gene.[3] Chromosome anomalies usually occur when there is an error in cell division following meiosis or mitosis. Chromosome abnormalities may be detected or confirmed by comparing an individual's karyotype, or full set of chromosomes, to a typical karyotype for the species via genetic testing. #snsinstitutions #snsdesignthinkers #snsdesignthinking

#Malefactorinfertility #genetics Talking about it, many factors are involved like - gene mutations - Y chromosome micro deletion - aneuploidy - chromosomal abnormalities are the common factors needed to be taken into consideration. it may lead to -azospermia -oligospermia -globozoospermia -macrospermia etc. none the less, DE NOVO, is commonly found impression for most of genetic studies. That only means -- "some biological processes has begun again". In simple language - " There is always a hope if you are that much desperate for results." BE POSITIVE. browse thro this link to get free access to our MFI[male factor infertility ]training https://lnkd.in/d9K7_x3m #infertilityawareness #ivftreatment #genetictesting #genemutations #Ayurved #ayurvedatreatment #treatmentoptions

Gene linkage explained Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction. ... Later work revealed that genes are physical structures related by physical distance. The typical unit of genetic linkage is the centimorgan \(cM\). Youtube video: https://lnkd.in/dSfMxfTQ \#nikolays_genetics_lessons

Thalassemia is a genetic disorder i.e. it is a disease which an individual inherits from parents. The number of red blood cells in the body is extremely low which is due to unavailability of the compound hemoglobin, that carries oxygen in the fluids. The mutation in the genetic material i.e. the DNA causes disruption in the normal production of the blood cells leading to anemia. Read more on: https://lnkd.in/d7yGv6it

Bicuspid aortic valve in monozygotic twins Genetic basis of BAV is well-established 🧬💖, showing a strong hereditary component. It primarily follows an autosomal dominant inheritance pattern with incomplete penetrance and variable expressivity. This means that not all individuals carrying the gene will exhibit the condition, and the severity can vary among those who do. In the context of twins👨👩👧👦, studies have shown that BAV can occur in both monozygotic (identical) 👯♂and dizygotic (fraternal) twins 👯♂. Monozygotic twins, who share the same genetic material, often exhibit discordant aortic valve morphology, meaning one twin may have BAV while the other does not. This highlights the role of other factors, possibly environmental 🌍 or epigenetic, in the development of BAV. #Echo #bicuspid #aortic #valve #monozygotictwins #genetic #diagnosis #echosingh #prime