The Scientist - Stem Cell Biology will derive stem cells from non-model organisms, conduct functional assays, and in vitro differentiation and characterization of stem cells for the purpose of species conservation. The candidate will be part of an innovative synthetic biology platform that will develop and optimize cells and assays to assess functionality of newly derived iPSCs/organoids/lineage differentiated cells.
**This position may be based out of Boston, MA or Dallas, TX**
Duties and Responsibilities:
Innovate then execute experiments to generate and differentiate iPSCs from non-model mammalian organisms, develop functional assays, assess and interpret experimental workflows
Test novel stem cell culture conditions, sort, screen, expand and differentiate iPSCs according to latest protocols and newly developed approaches
Work with team members to assess efficiency of workflows through cellular assays and NGS sequencing approaches
Work on project milestones
Attend lab meetings, prepare reports and presentations on the progress of projects
Great organizational skills and excellent laboratory record maintenance
Required Skills and Abilities:
Expert knowledge of iPSC derivation, differentiation, culture, propagation, and transfection methodologies
Experience in molecular biology (nucleic and protein extraction, gel electrophoresis) and cloning techniques (restriction enzyme-based cloning, Gibson assembly)
Experience with qPCR, flow cytometry, immunostaining, confocal microscopy
Experience with sequence analysis software
Experience with NGS library preparation and sequencing (Miseq, RNA-seq, WGS)
Strong written and oral communication skills, as well as creative problem-solving skills
Enjoys the fast-paced startup environment and teamwork
Practiced interpersonal and critical thinking skills.
Exceptional organizational skills and attention to detail.
Strong emotional intelligence and passion for building relationships across all levels of an organization.
Strong analytical and problem-solving skills.
Ability to function well in a growth-oriented, nimble environment.
Preferred Experience:
Postdoctoral work in stem cell biology
Previous work with gene editing technologies
Education and Experience:
PhD in biological sciences, stem cell biology, genetics or related field.
4+ years hands-on expertise in mammalian cell culture systems and iPSCs
What Colossal Offers You:
Medical, dental, and vision coverage
Unlimited PTO and company holidays so you can rest and recharge
Flexible spending accounts (FSA)
Company matched 401k retirement plan
Paid parental leave up to 12 weeks
Education reimbursement
An opportunity to help us return the Earth to a healthier state
The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in three locations that include laboratories, test facilities, academic institutions, libraries and offices. Dallas. Austin. Boston.
Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal.
Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.
EEO is the Law
Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle recruitment in-house.
Colossal is proud to be named a Best Place to Work by Built In across 4 categories in 2023 & 2024:
#1 on the 50 Best Startups to Work For in Dallas in 2023!
100 Best Midsize Places to Work in Dallas in 2024
100 Best Places to Work in Dallas, TX (All Size Employers) in 2024
100 Best Midsize Places to Work in Boston in 2024
Built In 2024 Award Lists
Great Place to Work Certification Page
Most Loved Workplace Certification Page
Seniority level
Mid-Senior level
Employment type
Full-time
Job function
Research, Analyst, and Information Technology
Industries
Biotechnology Research
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