Scientist II, Production Chemistry

JOB TITLE: Scientist II, Production Chemistry

DEPARTMENT: Operations

FOCUS: Chemistry, Production, Manufacturing

REPORTING: Production Manager and Tech Transfer Leader

LOCATION: Onsite, Madison, WI

Job Summary

For over 25 years, Mirus Bio pioneered the manufacture of transfection reagents and proprietary technologies for nucleic acid delivery applications. Despite our extensive experience, we pride ourselves on maintaining the spirit of a startup. Our dynamic and forward-thinking approach has allowed us to stay agile and adapt to emerging trends. Our work is technical and cutting-edge, and we promote a culture of that encourages creativity, initiative, responsibility, and respect. Our team members are engaged and motivated by the desire to support our customers to practice good science to generate strong results. Mirus, together with Gamma Biosciences, is establishing the future of science and medicine by developing products that enable researchers within the cell and gene therapy space.

OUR MISSION: Empower Discovery. Enable Innovation. Improve Life.

We are seeking a full-time onsite Scientist II, Production Chemistry to be the technical team member supporting the Production Chemistry Team for Mirus Bio’s products including in vitro transfection reagents, nucleic acid labeling reagents, and accessory products. This individual contributor position will take a hands-on role in the synthesis and analysis of compounds, and a lead role in streamlining processes, updating work instructions, and improving overall production chemistry processes to support the synthesis and analysis of compounds that are utilized in Mirus products. This position will report to the Production Manager and Tech Transfer Leader and work closely with Quality, Technical Support, Shipping and R&D departments. The Scientist II, Production Chemistry is expected to possess an extensive understanding of laboratory procedures and the ability to conduct work within cGMP guidelines, when applicable.

We are currently on the lookout for a pro-active individual to join our passionate team. If you are someone who thrives in a collaborative, innovative, and fast-paced environment, join us in shaping the future of our industry and be a part of a team that continues to redefine possibilities. This is a full-time on-site position. This role works cross-functionally with all departments within Mirus Bio.

Duties & Responsibilities

• Technical team member supporting the Production Chemistry Team
• Perform critical production and lab support functions including synthesis of lipids, polymers, and small molecules for Mirus Bio products. Extensively characterize compounds using various physical and chemical characterization techniques such gel permeation chromatography (GPC), dynamic light scattering (DLS), nuclear magnetic resonance spectroscopy (NMR), high performance liquid chromatography (HPLC), fluorescence, mass spectrometry (MS), Infra-red spectroscopy (FT-IR)
• Demonstrate thought leadership. Identify opportunities for improvement and minimize errors by applying technical skills and critical thinking.
• Respond quickly to changing priorities and balance being a Team Member of multiple projects (including partnerships with external CMOs, projects with external test labs, internal tech transfers, cGMP method development, etc.) with potentially overlapping deadlines
• Monitor inventory levels of raw materials to support production schedule and assist in ordering and receiving Production RUO and cGMP materials into inventory as needed
• Maintain complete and thorough documentation including writing SOPs and updating existing documents as processes change.
• Responsible for Technical Review of external CMO and external test lab batch records as needed
• Write deviations and change controls as required
• Participate in root cause analysis and drive continuous improvement.
• Communication across multiple teams to eliminate barriers and ensure alignment with upstream and downstream partners
• Follow GDP and cGMP guidelines and ensure quality compliance.
• Build positive relationships during internal and external interactions
• Demonstrate behavior outlined within the Mirus Bio Employee Handbook.
• Perform other duties as assigned by Production Manager and Tech Transfer Leader
  
  

REQUIREMENTS

Education:

• Requires a Bachelor’s or Advanced degree in Chemistry, or other related discipline, or commensurate work experience
  
  

Professional:

• A minimum of 5 years of relevant experience working in a laboratory synthesizing and characterizing organic and/or polymer compounds
• Capability to work in an organized manner, to make critical observations, and to maintain good records of the results.
• Excellent verbal and written communication skills required
• Demonstrated ability to identify and solve problems
• Ability to work productively in a team environment
• Ability to work in a laboratory setting and lift 35 lbs. occasionally. Repetitive motion may be a work environment stressor for this position
• Demonstrated experience with technical writing including investigations, ability to modify and complete manufacture batch records and SOPs in an industry setting
• Hands on experience with a variety of analytical techniques, including NMR, GPC/SEC, fluorescence, FT-IR, MS, UV-vis, HPLC, etc
• Previous experience working for a life sciences company and in a cGMP, environment is preferred
  
  

Travel Requirements:

• Ability to travel independently 5% of the time, including overnight travel.
• Ability to drive a vehicle; Must have current and valid U.S. driver license
  
  

This position has a salary range of $75,000 - $95,000 per year and will be commensurate with experience.

OUR CORE VALUES

Mirus Core Values:

• Empower
• Passion
• Integrity
• Compassion
• Collaboration
• Innovation
  
  

Our passion is at the heart of our mission to give our customers and the scientific community the best transfection products, methods, and applications.

Mirus benefits include non-compensation benefits like health care, paid time off, retirement savings, and professional development.

Mirus Bio is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.

This applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, and training. Mirus Bio makes hiring decisions based solely on qualifications, merit, and business needs at the time.

The preceding functions have been provided as examples of the types of work performed by employees assigned to this job classification. Management reserves the right to add, modify, change, or rescind work assignments and to make reasonable accommodations as needed. To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The job requirements for the positions listed above are representative of the knowledge, skills and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

EEO/AA Statement

Mirus Bio is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.

This applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits and training. Mirus Bio makes hiring decisions based solely on qualifications, merit, and business needs at the time.

Accommodation Statement

Mirus Bio is committed to the inclusion of all qualified individuals in the hiring process, including but not limited to those with disabilities. If you require reasonable accommodation(s) to participate in the application or interview process, please contact

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