"We need to develop these genotypes that will be resistant to these increased stresses. The approaches we're developing are sort of agnostic as to species," Whitehead Institute Member Mary Gehring says. Full video on our YouTube channel: https://lnkd.in/ek3mf2FU
Whitehead Institute
Research Services
Cambridge, Massachusetts 10,896 followers
A world-renowned non-profit research institution dedicated to improving human health through basic biomedical research
About us
Whitehead Institute for Biomedical Research is a leading, nonprofit research and educational institution that has defined the cutting edge of biomedical science, creating a legacy of research excellence and academic eminence since 1982. Wholly independent in its governance, finances and research programs, Whitehead shares a teaching affiliation with Massachusetts Institute of Technology, offering the intellectual, collegial and scientific benefits of a leading research university. Whitehead provides scientists with the resources and freedom to follow their scientific instincts, form novel collaborations and conduct high-risk research. While probing basic biological processes, 14 faculty Members and 6 Fellows develop innovative technologies and lay the foundation for projects that improve human health. They run pioneering programs in cancer research, immunology, developmental biology, stem cell research, regenerative medicine, genetics and genomics—programs with a record of success.
- Website
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http://www.wi.mit.edu
External link for Whitehead Institute
- Industry
- Research Services
- Company size
- 201-500 employees
- Headquarters
- Cambridge, Massachusetts
- Type
- Nonprofit
- Founded
- 1982
- Specialties
- biomedical Research, cancer research, immunology, developmental biology, stem cell research, regenerative medicine, genetics, genomics, evolution, protein funtion, and RNA
Locations
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Primary
455 Main St
Cambridge, Massachusetts 02142, US
Employees at Whitehead Institute
Updates
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Small changes in the molecular machines that carry out RNA interference can lead to big differences in the efficacy of gene silencing. These new findings from the Bartel lab have implications for the design of gene-silencing therapeutics: https://lnkd.in/eFmMZu2M
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"I felt that asking the right questions at the right time in the right place is more important to me than following a specific kind of template," postdoc Kutay Deniz Atabay says. #WhiteheadPostdocProfiles https://lnkd.in/e_7aYX8D
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Condensates not only store maternal mRNA within the germ cell but also play an active role in the translation of specific mRNAs. New findings from the Lehmann lab: https://lnkd.in/exVE-CgA
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Researchers in the Lourido lab performed the first genome-wide screen of Toxoplasma gondii in live hosts, revealing genes that are important for infection but previously undetected in cell culture experiments: https://lnkd.in/e6CeHKTh
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"CHARMs are an elegant solution to the problem of silencing disease genes, and they have the potential to have an important position in the future of genetic medicines," Whitehead Institute Member Jonathan Weissman says. https://lnkd.in/gmuNXmYa
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Researchers in the Weissman lab and collaborators at the Broad Institute have developed a gene-silencing tool that shows promise as a therapy against fatal prion diseases. The tool, called CHARM, paves the way for a new class of genetic approaches to treat certain diseases. https://lnkd.in/gmuNXmYa
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Our latest #DayintheLab features Neha Bokil, a graduate student in the Page lab studying sex chromosomes' impact on gene regulation: https://lnkd.in/evdhmdEH
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Carly Martin studied neuroscience during her undergrad, but made a big leap to plant science when she began her PhD at Whitehead Institute. Follow Carly as she spends a #DayintheLab: https://lnkd.in/egXudY4g
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Whitehead Institute Member Siniša Hrvatin has been named a 2024 McKnight Scholar, supporting his research on mechanisms underlying certain animals’ capacity to enter states of torpor and hibernation. Congratulations, Siniša! https://lnkd.in/gFr8X372
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