We're #hiring a new Senior/Research Associate, Functional Genomics in South San Francisco, California. Apply today or share this post with your network.
NewLimit
Biotechnology Research
South San Francisco, California 2,939 followers
NewLimit is a biotechnology company working to extend human healthspan by developing epigenetic reprogramming therapies.
About us
NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale.
- Website
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https://newlimit.com
External link for NewLimit
- Industry
- Biotechnology Research
- Company size
- 11-50 employees
- Headquarters
- South San Francisco, California
- Type
- Privately Held
- Founded
- 2022
Locations
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Primary
Get directions
South San Francisco, California 94080, US
Employees at NewLimit
Updates
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We're #hiring a new Scientist/Senior Scientist, Immunology in South San Francisco, California. Apply today or share this post with your network.
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Updates from the early summer months at NewLimit: We reprogrammed old, human cells to look younger based on their genomic profiles. Now we need to make them act younger based on their function. We've made progress on building the tools to measure these functional improvments. Highlights by the numbers (quarter/quarter): - 2X lower cost per TF set we test - 1.5X the # of TF sets that reverse phenotypic age in real, human cells - +4 functional assays for hepatocytes, +1 for T cells - +3 team members All in our latest blog: https://lnkd.in/gT9bDDVb
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We're excited to share that Markus Grompe, M.D. has joined our Scientific Advisory Board to guide our hepatic metabolism program at NewLimit! Markus' work has provided much of the foundational knowledge and technology critical for our program to reverse the metabolic decline that comes with age. In addition to his scientific accomplishments, Markus brings a unique perspective to our SAB as a serial biotech founder. We look forward to working with him for years to come.
Markus Grompe is joining our Scientific Advisory Board
blog.newlimit.com
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NewLimit reposted this
We shared our annual Progress Update at NewLimit last week. We've been moving quickly to develop medicines that restore youthful function in old cells by partial reprogramming, and we're excited to share some of the discoveries we've made along the way. Tune in to check out a few highlights: - Tested 200X more sets of partial reprogramming factors than the field (that we know of) - Cut the cost of our reprogramming screens by >3X, reduced cycle times by 2X - Built performant models to measure cell age from cell genomics profiles - Discovered >20 reprogramming factor sets that restore youthful phenotypes in old cells - Found that many effects of partial reprogramming are durable - Developed 7 functional assays, added 1 therapeutic program, and found our first age-discriminating functional approaches https://lnkd.in/gh6G5Vrf Our cast includes: Brian Armstrong, Burak Dura, Gregory Johnson, John Leonard, Blake Byers, & myself We're always looking to bring talented scientists & engineers onto our team. Please reach out if any of our open roles are exciting to you or a colleague!
NewLimit - YouTube
youtube.com
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We'll be sharing some of our recent work at NewLimit during our Progress Update today at 5pm PT, both in-person and via livestream. We'd love to hear your questions in Q&A at the end! livestream.newlimit.com
NewLimit Progress Update 2024
https://www.youtube.com/
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We're #hiring a new Scientist, Metabolism in South San Francisco, California. Apply today or share this post with your network.
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We're #hiring a new Automation Engineer in South San Francisco, California. Apply today or share this post with your network.
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We're #hiring a new Scientist, In Vivo Physiology in South San Francisco, California. Apply today or share this post with your network.
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We've recently opened a new role at NewLimit focused on building pre-clinical models to support our therapeutic program in hepatic metabolism. This is an exciting opportunity to work on the frontier of functional genomics & humanized model systems to develop a new class of reprogramming medicines. You'll have a broad impact from the earliest phases of discovery all the way through pre-clinical development. Please reach out if you or a colleague are interested! https://lnkd.in/gj5TCCbr
Scientist, In Vivo Physiology
boards.greenhouse.io