Duke Clinical Research Institute

New study results have shown bariatric surgery and the weight loss drug tirzepatide can help reduce obstructive sleep apnea. For DCRI's Nishant Shah, there is an "urgency to aggressively battle obesity" in the U.S., and results like these support the idea of treating OSA and other cardiometabolic parameters in various clinical settings. Learn more: https://lnkd.in/efjtJr4c #sleepapnea #obesity #clinicaltrials #clinicalresearch

During a secondary analysis of the ADAPTABLE trial, experts including the DCRI’s Lisa Wruck, Adrian Hernandez, and Schuyler Jones found no major sex-specific differences regarding safety and effectiveness when taking two aspirin doses for the secondary prevention of ASCVD events. Read the full report here: https://lnkd.in/eZU2vPjt #clinicaltrials #clinicalresearch #ASCVD #hearthealth

Have you noticed your heart beating faster when standing up or bending down? As DCRI’s Jonathan Piccini, MD, MHS explains, this is due to the blood flow into the right side of the heart changing, which can in turn cause extra beats. While this is normal for many, for others, this can be a potential indicator of postural tachycardia syndrome. Read more to see what Dr. Piccini and other experts have to say about spotting the signs of POTS and what treatment options are available: https://lnkd.in/eMKCdwrA #hearthealth #POTS #cardiology

By using data from the Project Baseline Health Study’s investigational wearable devices, DCRI’s Jessilyn Dunn, Svati Shah, Melissa Daubert, Pamela Douglas, and other researchers have gathered new evidence on how walking behaviors can potentially indicate signs of early-stage heart failure. Read more about how these wearables could help compliment clinical testing for identifying and monitoring pre-symptomatic HF: https://lnkd.in/eVDc8aXv #clinicaltrials #clinicalresearch #wearables #heartfailure

In the past 100 years, cardiovascular disease research and treatment has undergone massive changes. But what will the next 100 years hold? DCRI's Adrian Hernandezz joins other experts to discuss three key areas that they expect to be important factors in the next century: https://lnkd.in/eXVpHKnZ #clinicalresearch #clinicaltrials #cardiology #heartdisease

Congratulations to our 2024 Career Service Award recipients! This year, we had 102 recipients representing a combined 1,675 years of service. Join us in giving them a big thank you for their years of fantastic work! #clinicaltrials #clinicalresearch #employeeappreciation #careerservice

Even with decades of research, questions remain about optimal risk-communication approaches, which can be necessary in applications such as discrete choice experiments. As part of a new project for the FDA, Matthew Wallace, Jui-Chen Yang, Jessie Sutphin, Reed Johnson, Juan Marcos González Sepúlveda, and Shelby Reed compared the effects of 3 design factors while conducting a patient preference survey for devices used for peripheral artery disease treatment and their potential risks. Read more about the results here: https://lnkd.in/evZxXGEF #clinicaltrials #clinicalresearch #arterydisease

Timely usage of AEDs is key for improving out-of-hospital cardiac arrest survival rates. Yet for many communities, access to these devices remains a significant barrier. DCRI faculty member Monique Starks is working to use drones to improve delivery times for AEDs to ensure they arrive within that key five-minute window. Check out the video below for a demonstration of the drone delivery in action, and be sure to read the latest study results published in the American College of Cardiology: https://lnkd.in/gGhJWed5 #clinicaltrials #clinicalresearch #AEDs #heartattack

These days, a single patient can generate 80 megabytes yearly in imaging and electronic health data. DCRI’s Adrian Hernandez discusses how an integrated system from data generation to implementation can help care providers manage this massive data influx, leading to better outcomes for patients, especially in terms of cardiovascular health: https://lnkd.in/dvMZiUSC #clinicalresearch #datamanagement #cardiology #healthdata

As award recipients of the Duke Clinical and Translational Science Institute and Children’s Health & Discovery Initiative's pilot Child Health Equity Program, DCRI members Jason Lang and Kevin Hill are working to improve health outcomes for children and their families and connect with community partners. Learn more about the initiative and their work here: https://lnkd.in/gKx4cN_T #clinicaltrials #clinicalresearch #pediatrics #childcare