Diffuse Bio

I’m excited to share some of our progress at Diffuse Bio today, about a year and a half into our journey! At Diffuse, we’re building generative AI for protein design. Our mission is to build AI that engineers new and useful proteins with unprecedented control and accuracy. Today we introduce Diffuse StructGen-1 (DSG-1), a new foundation model for protein design. We prompted DSG-1 to design nanobody binders, a therapeutically relevant class of proteins. Remarkably, DSG-1 designs bound the target with a 3% hit rate, about seven orders of magnitude better than industry-standard discovery approaches. Importantly, we are able to design strong binders (<=10nM range) – a significant advance over previous work. More details can be found in our blog post linked below! We are in the early stages of AI development in molecular design, and we envision a future where AI enables rapid and accurate design of any protein. If our mission resonates with you please reach out at hello@diffuse.bio.

I’m excited to share some of our progress at Diffuse Bio today, about a year and a half into our journey! At Diffuse, we’re building generative AI for protein design. Our mission is to build AI that engineers new and useful proteins with unprecedented control and accuracy. Today we introduce Diffuse StructGen-1 (DSG-1), a new foundation model for protein design. We prompted DSG-1 to design nanobody binders, a therapeutically relevant class of proteins. Remarkably, DSG-1 designs bound the target with a 3% hit rate, about seven orders of magnitude better than industry-standard discovery approaches. Importantly, we are able to design strong binders (<=10nM range) – a significant advance over previous work. More details can be found in our blog post linked below! We are in the early stages of AI development in molecular design, and we envision a future where AI enables rapid and accurate design of any protein. If our mission resonates with you please reach out at hello@diffuse.bio.

I’m excited to share some of our progress at Diffuse Bio today, about a year and a half into our journey! At Diffuse, we’re building generative AI for protein design. Our mission is to build AI that engineers new and useful proteins with unprecedented control and accuracy. Today we introduce Diffuse StructGen-1 (DSG-1), a new foundation model for protein design. We prompted DSG-1 to design nanobody binders, a therapeutically relevant class of proteins. Remarkably, DSG-1 designs bound the target with a 3% hit rate, about seven orders of magnitude better than industry-standard discovery approaches. Importantly, we are able to design strong binders (<=10nM range) – a significant advance over previous work. More details can be found in our blog post linked below! We are in the early stages of AI development in molecular design, and we envision a future where AI enables rapid and accurate design of any protein. If our mission resonates with you please reach out at hello@diffuse.bio.