Statistically powerful clinical trials with medical imaging AI

Quantitative evaluation of medical images plays an increasingly important role in research and clinical trials for drug development. Imaging-based outcomes reveal deeper insights into pulmonary diseases and allow for an earlier identification of abnormalities, with much better accuracy and precision, in comparison to traditional pulmonary function test methods. Our advanced solutions for AI-powered chest CT analysis provide a fast and detailed quantitative assessment of all major lung and respiratory pathologies.

Wide range of extensively validated and novel measurements

Our modular platform contains generalizable deep learning models developed for anatomical and disease-related quantification tasks in a multitude of diseases.

Advanced anatomical segmentation algorithms of the lungs, lobes, pulmonary (sub)segments, interlobar fissures, airways and anatomical branches, pulmonary arteries and pulmonary veins allow for very precise and detailed exploration of local lung pathologies for both common and rare pulmonary diseases such as COPD, Asthma, COVID-19, Cystic Fibrosis, Interstitial Lung Disease, Pulmonary Arterial Hypertension and more.

Thirona's artificial intelligence-based quantification capabilities for chest CT analysis, include:

  • Anatomical measures such as: volumes of each anatomical structure, parenchymal density evaluation, bronchial and vascular dimensions, bronchus-artery analysis (BA), fissure completeness, artery-vein phenotyping (AVX), etc.
  • Disease-related severity and distribution assessment for: emphysema, air trapping, bronchial wall thickening, bronchial and vascular dropout, covid-19 infection, bronchiectasis, fibrosis, mucous impaction, atelectasis, CT-approximated perfusion (PXT) and ventilation defects, pulmonary vascular enlargement, etc.

Supporting the full process towards optimal end results

  • CUSTOM TRIAL DESIGN

    Measurements precisely tailored to patient populations | Image acquisition requirements to ensure reproducible results | Effective inclusion criteria

  • OPTIMIZATION OF DATA REPRODUCIBILITY

    Normalization of incoming CT scans for reproducible quantitative assessment | AI Algorithms designed to handle data variation

  • ADVANCED IMAGE ANALYSIS LungQ™

    Wide range of exploratory and cleared measurements | Specialized Image Analysis Service for complex assessments | Pivotal markers approved for
    clinical use in Europe, UK, USA and Australia

  • DOUBLE QUALITY REVIEW

    ISO 13485 certified quality assurance process | 2-step quality review by human analysts

  • RESULTS INTERPRETATION

    Quantitative and 3D visual representation of outcomes | Imaging Expert Assistance for outcome interpretation

Certified solution

LungQ 3.0.0 clinical software package

Approved for clinical use in Europe and USA

The Thirona’s LungQ v3.0.0 software produces CT values for pulmonary tissue, providing quantitative support for diagnosis and follow-up examinations. LungQ can be used to support the physician in the diagnosis, evaluation and documentation of pulmonary tissue images (e.g. abnormalities) from CT thoracic datasets. The analysis provided includes segmentation and isolation of sub-compartments, volumetric analysis, density evaluations, fissure evaluation and reporting tools.

LungQ v3.0.0 clinical software is FDA 510(k) cleared and a certified as a class IIb medical device CE marked (CE 0344) under the European Medical Devices Regulation (EU-MDR 217/745). The CE certified version provides additional analysis of tissue destruction and airway and vessels evaluation.

Partnering for the shortest path to the highest quality imaging endpoints​


Clinical trials often face unique challenges, from patient phenotyping and defining the best fit-for-purpose measurement, up to delivering robust evidence – it all needs to be done with no compromise to make sure trials are effective. ​

Our integral approach ensures fast and reliable delivery of precise imaging endpoints, while minimizing costs and time-to-market. ​

Full scope imaging service​

In partnership with Voiant, a clinical trial imaging solution provider, we offer a fully integrated service allowing to run clinical trials with imaging effectively, while minimizing risk of trial failure and saving on operational expenses. ​
With the unique benefit of our combined expertise in lung image analysis and clinical research, proven technology platform and well-guarded quality assurance process along the whole trial, we can guarantee robust results at any scale, with consistent output quality. One integral approach, one platform, one contractor for seamless operations and reliable execution.

Ready to apply AI image analysis to get better outcomes faster?


Let’s explore how we can work together!​

Sanaz Berahmani

Business Development Manager

Ready to apply AI image analysis to get better outcomes faster?


Let’s explore how we can work together!​

Carla Kalkhoven

Business development manager for clinical trials