Using python 2.7 on windows 7 64 bit machine. 
How to get a file close event:
1. when file is opened in a new process of file opener(like notepad, wordpad which opens file everytime in new process of wordpad)
2. when file is opened in a tab of file opener(like notepad++, which opens all files in new tab but there exist only a single process of notepad++ running)

So, how to get file close event in above cases. Is it possible to achieve above cases through  a common code. I an dealing with different file types