This is my solution.

<form enctype="multipart/form-data">    

    <div class="form-group">
        <label class="control-label col-md-2" for="apta_Description">Description</label>
        <div class="col-md-10">
            <input class="form-control text-box single-line" id="apta_Description" name="apta_Description" type="text" value="">
        </div>
    </div>

    <input name="file" type="file" />
    <input type="button" value="Upload" />
</form>

and the js

<script>

    $(':button').click(function () {
        var formData = new FormData($('form')[0]);
        $.ajax({
            url: '@Url.Action("Save", "Home")',  
            type: 'POST',                
            success: completeHandler,
            data: formData,
            cache: false,
            contentType: false,
            processData: false
        });
    });    

    function completeHandler() {
        alert(":)");
    }    
</script>

Controller

[HttpPost]
public ActionResult Save(string apta_Description, HttpPostedFileBase file)
{
    return Json(":)");
}

This is my solution.

<form enctype="multipart/form-data">    

    <div class="form-group">
        <label class="control-label col-md-2" for="apta_Description">Description</label>
        <div class="col-md-10">
            <input class="form-control text-box single-line" id="apta_Description" name="apta_Description" type="text" value="">
        </div>
    </div>

    <input name="file" type="file" />
    <input type="button" value="Upload" />
</form>

and the js

<script>

    $(':button').click(function () {
        var formData = new FormData($('form')[0]);
        $.ajax({
            url: '@Url.Action("Save", "Home")',  
            type: 'POST',                
            success: completeHandler,
            data: formData,
            cache: false,
            contentType: false,
            processData: false
        });
    });    

    function completeHandler() {
        alert(":)");
    }    
</script>

Controller

[HttpPost]
public ActionResult Save(string apta_Description, HttpPostedFileBase file)
{
    [...]
}

This is my solution for mvc using ajax.

<form enctype="multipart/form-data">    

    <div class="form-group">
        <label class="control-label col-md-2" for="apta_Description">Description</label>
        <div class="col-md-10">
            <input class="form-control text-box single-line" id="apta_Description" name="apta_Description" type="text" value="">
        </div>
    </div>

    <input name="file" type="file" />
    <input type="button" value="Upload" />
</form>

and the js

<script>

    $(':button').click(function () {
        var formData = new FormData($('form')[0]);
        $.ajax({
            url: '@Url.Action("Save", "Home")',  
            type: 'POST',                
            success: completeHandler,
            data: formData,
            cache: false,
            contentType: false,
            processData: false
        });
    });    

    function completeHandler() {
        alert(":)");
    }    
</script>

Controller

[HttpPost]
public ActionResult Save(string apta_Description, HttpPostedFileBase file)
{
    return Json(":)");
}

This is my solution.

<form enctype="multipart/form-data">    

    <div class="form-group">
        <label class="control-label col-md-2" for="apta_Description">Description</label>
        <div class="col-md-10">
            <input class="form-control text-box single-line" id="apta_Description" name="apta_Description" type="text" value="">
        </div>
    </div>

    <input name="file" type="file" />
    <input type="button" value="Upload" />
</form>

and the js

<script>

    $(':button').click(function () {
        var formData = new FormData($('form')[0]);
        $.ajax({
            url: '@Url.Action("Save", "Home")',  
            type: 'POST',                
            success: completeHandler,
            data: formData,
            cache: false,
            contentType: false,
            processData: false
        });
    });    

    function completeHandler() {
        alert(":)");
    }    
</script>

Controller

[HttpPost]
public ActionResult Save(string apta_Description, HttpPostedFileBase file)
{
    return Json(":)");
}