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    $\begingroup$ Do note that the "getting back" part is the expensive one - in space, you don't get discounts for return tickets. Getting a pound of stuff back requires bringing 5-10 pounds of stuff there; so a one-way mission costs no more than 10%-20% of a two-way mission of similar size. $\endgroup$
    – Peteris
    Commented Nov 5, 2014 at 15:24
  • $\begingroup$ Sure, but nobody is realistically going to mount a one-way mission to Mars anytime soon (Mars one will never leave the ground). Nevertheless, most of the tech we would need already exists and has been proven out. I personally think the hardest part will be developing the lander and Mars-to-orbit launcher and in-situ fuel synthesis. Both are technical challenges. $\endgroup$
    – Kirkaiya
    Commented Nov 6, 2014 at 18:40