From Wiki Replicator article:

A replicator can create any inanimate matter, as long as the desired molecular structure is on file, but it cannot create antimatter, dilithium, latinum, or a living organism of any kind; in the case of living organisms, non-canon works such as the Star Trek: the Next Generation Technical Manual state that, though the replicators use a form of transporter technology, it's at such a low resolution that creating living tissue is a physical impossibility.

 

...

 

However, unlike transporters, which duplicate matter at the quantum level, replicators must be capable of a large number of different materials on demand. If patterns were to be stored at the quantum level, an impossible amount of data storage (or a set of original copies of the materials) would be required. To resolve this, patterns are stored in memory at the molecular level.

 

The drawback of doing so is that it is impossible to replicate objects with complicated quantum structures, such as living beings, dilithium, or latinum. In reality, neither living beings nor the cited elements do necessarily have a quantum structure inherently more complicated than other things. In the TNG episode "Allegiance", aliens used their version of replicators to create a Picard impostor. Additionally, read/write errors cause a number of single-bit errors to occur in replicated materials. Though usually undetectable to human senses, computer scanning can be used to reveal these discrepancies, and they may explain the frequent complaint (by some gourmets and connoisseurs) that replicated food and beverages suffer from substandard taste. These errors also may cause a nontoxic material to become toxic when replicated, or create strains of deadly viruses and bacteria from previously harmless ones.

From Wiki Replicator article:

A replicator can create any inanimate matter, as long as the desired molecular structure is on file, but it cannot create antimatter, dilithium, latinum, or a living organism of any kind; in the case of living organisms, non-canon works such as the Star Trek: the Next Generation Technical Manual state that, though the replicators use a form of transporter technology, it's at such a low resolution that creating living tissue is a physical impossibility.

...

However, unlike transporters, which duplicate matter at the quantum level, replicators must be capable of a large number of different materials on demand. If patterns were to be stored at the quantum level, an impossible amount of data storage (or a set of original copies of the materials) would be required. To resolve this, patterns are stored in memory at the molecular level.

The drawback of doing so is that it is impossible to replicate objects with complicated quantum structures, such as living beings, dilithium, or latinum. In reality, neither living beings nor the cited elements do necessarily have a quantum structure inherently more complicated than other things. In the TNG episode "Allegiance", aliens used their version of replicators to create a Picard impostor. Additionally, read/write errors cause a number of single-bit errors to occur in replicated materials. Though usually undetectable to human senses, computer scanning can be used to reveal these discrepancies, and they may explain the frequent complaint (by some gourmets and connoisseurs) that replicated food and beverages suffer from substandard taste. These errors also may cause a nontoxic material to become toxic when replicated, or create strains of deadly viruses and bacteria from previously harmless ones.

From Wiki Replicator article:

A replicator can create any inanimate matter, as long as the desired molecular structure is on file, but it cannot create antimatter, dilithium, latinum, or a living organism of any kind; in the case of living organisms, non-canon works such as the Star Trek: the Next Generation Technical Manual state that, though the replicators use a form of transporter technology, it's at such a low resolution that creating living tissue is a physical impossibility.

...

However, unlike transporters, which duplicate matter at the quantum level, replicators must be capable of a large number of different materials on demand. If patterns were to be stored at the quantum level, an impossible amount of data storage (or a set of original copies of the materials) would be required. To resolve this, patterns are stored in memory at the molecular level.

The drawback of doing so is that it is impossible to replicate objects with complicated quantum structures, such as living beings, dilithium, gold, or latinum. (However, in the TNG episode "Allegiance", aliens used their version of replicators to create a Picard impostor.) Additionally, read/write errors cause a number of single-bit errors to occur in replicated materials. Though usually undetectable to human senses, computer scanning can be used to reveal these discrepancies, and they may explain the frequent complaint (by some gourmets and connoisseurs) that replicated food and beverages suffer from substandard taste. These errors also may cause a nontoxic material to become toxic when replicated, or create strains of deadly viruses and bacteria from previously harmless ones.

From Wiki Replicator article:

A replicator can create any inanimate matter, as long as the desired molecular structure is on file, but it cannot create antimatter, dilithium, latinum, or a living organism of any kind; in the case of living organisms, non-canon works such as the Star Trek: the Next Generation Technical Manual state that, though the replicators use a form of transporter technology, it's at such a low resolution that creating living tissue is a physical impossibility.

...

However, unlike transporters, which duplicate matter at the quantum level, replicators must be capable of a large number of different materials on demand. If patterns were to be stored at the quantum level, an impossible amount of data storage (or a set of original copies of the materials) would be required. To resolve this, patterns are stored in memory at the molecular level.

The drawback of doing so is that it is impossible to replicate objects with complicated quantum structures, such as living beings, dilithium, or latinum. In reality, neither living beings nor the cited elements do necessarily have a quantum structure inherently more complicated than other things. In the TNG episode "Allegiance", aliens used their version of replicators to create a Picard impostor. Additionally, read/write errors cause a number of single-bit errors to occur in replicated materials. Though usually undetectable to human senses, computer scanning can be used to reveal these discrepancies, and they may explain the frequent complaint (by some gourmets and connoisseurs) that replicated food and beverages suffer from substandard taste. These errors also may cause a nontoxic material to become toxic when replicated, or create strains of deadly viruses and bacteria from previously harmless ones.