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Table representation of search results timeline featuring number of search results per year.
Year
Number of Results
1964
4
1965
16
1966
29
1967
25
1968
19
1969
21
1970
13
1971
16
1972
20
1973
17
1974
13
1975
8
1976
10
1977
9
1978
12
1979
12
1980
10
1981
6
1982
9
1983
4
1984
14
1985
7
1986
7
1987
8
1988
5
1989
9
1990
5
1991
10
1992
7
1993
6
1994
5
1995
8
1996
10
1997
6
1998
4
1999
4
2000
9
2001
12
2002
7
2003
10
2004
7
2005
15
2006
13
2007
16
2008
15
2009
13
2010
20
2011
20
2012
31
2013
38
2014
28
2015
23
2016
27
2017
28
2018
38
2019
28
2020
28
2021
24
2022
17
2023
14
2024
18
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Page 1
2-Oxoglutarate-dependent dioxygenases in cancer.
Losman JA, Koivunen P, Kaelin WG Jr.
Losman JA, et al.
Nat Rev Cancer. 2020 Dec;20(12):710-726. doi: 10.1038/s41568-020-00303-3. Epub 2020 Oct 21.
Nat Rev Cancer. 2020.
PMID: 33087883
Review.
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Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.
Xu W, Yang H, Liu Y, Yang Y, Wang P, Kim SH, Ito S, Yang C, Wang P, Xiao MT, Liu LX, Jiang WQ, Liu J, Zhang JY, Wang B, Frye S, Zhang Y, Xu YH, Lei QY, Guan KL, Zhao SM, Xiong Y.
Xu W, et al.
Cancer Cell. 2011 Jan 18;19(1):17-30. doi: 10.1016/j.ccr.2010.12.014.
Cancer Cell. 2011.
PMID: 21251613
Free PMC article.
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2-Oxoglutarate-Dependent Oxygenases.
Islam MS, Leissing TM, Chowdhury R, Hopkinson RJ, Schofield CJ.
Islam MS, et al.
Annu Rev Biochem. 2018 Jun 20;87:585-620. doi: 10.1146/annurev-biochem-061516-044724. Epub 2018 Mar 1.
Annu Rev Biochem. 2018.
PMID: 29494239
Review.
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α-Ketoglutarate inhibits autophagy.
Baracco EE, Castoldi F, Durand S, Enot DP, Tadic J, Kainz K, Madeo F, Chery A, Izzo V, Maiuri MC, Pietrocola F, Kroemer G.
Baracco EE, et al.
Aging (Albany NY). 2019 Jun 7;11(11):3418-3431. doi: 10.18632/aging.102001.
Aging (Albany NY). 2019.
PMID: 31173576
Free PMC article.
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