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Table representation of search results timeline featuring number of search results per year.
Year
Number of Results
1977
1
1978
4
1979
13
1980
23
1981
69
1982
136
1983
70
1984
90
1985
151
1986
267
1987
474
1988
666
1989
788
1990
821
1991
778
1992
750
1993
722
1994
656
1995
614
1996
586
1997
464
1998
441
1999
407
2000
391
2001
356
2002
353
2003
308
2004
255
2005
260
2006
218
2007
223
2008
221
2009
216
2010
187
2011
207
2012
205
2013
161
2014
172
2015
126
2016
143
2017
112
2018
94
2019
78
2020
88
2021
88
2022
79
2023
75
2024
35
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Page 1
Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report.
Rosenberg SA, Packard BS, Aebersold PM, Solomon D, Topalian SL, Toy ST, Simon P, Lotze MT, Yang JC, Seipp CA, et al.
Rosenberg SA, et al.
N Engl J Med. 1988 Dec 22;319(25):1676-80. doi: 10.1056/NEJM198812223192527.
N Engl J Med. 1988.
PMID: 3264384
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Interleukin-2 toxicity.
Siegel JP, Puri RK.
Siegel JP, et al.
J Clin Oncol. 1991 Apr;9(4):694-704. doi: 10.1200/JCO.1991.9.4.694.
J Clin Oncol. 1991.
PMID: 2066765
Review.
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Interleukin-2 and leukemia.
Goodman M, Cabral L, Cassileth P.
Goodman M, et al.
Leukemia. 1998 Nov;12(11):1671-5. doi: 10.1038/sj.leu.2401199.
Leukemia. 1998.
PMID: 9823939
Review.
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Recombinant interleukin-2.
Bruton JK, Koeller JM.
Bruton JK, et al.
Pharmacotherapy. 1994 Nov-Dec;14(6):635-56.
Pharmacotherapy. 1994.
PMID: 7885967
Review.
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Interleukin 2.
Hamblin TJ.
Hamblin TJ.
BMJ. 1990 Feb 3;300(6720):275-6. doi: 10.1136/bmj.300.6720.275.
BMJ. 1990.
PMID: 2106954
Free PMC article.
Review.
No abstract available.
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Low dose interleukin-2 selectively expands circulating regulatory T cells but fails to promote liver allograft tolerance in humans.
Lim TY, Perpiñán E, Londoño MC, Miquel R, Ruiz P, Kurt AS, Kodela E, Cross AR, Berlin C, Hester J, Issa F, Douiri A, Volmer FH, Taubert R, Williams E, Demetris AJ, Lesniak A, Bensimon G, Lozano JJ, Martinez-Llordella M, Tree T, Sánchez-Fueyo A.
Lim TY, et al.
J Hepatol. 2023 Jan;78(1):153-164. doi: 10.1016/j.jhep.2022.08.035. Epub 2022 Sep 7.
J Hepatol. 2023.
PMID: 36087863
Free article.
Clinical Trial.
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Managing toxicities of high-dose interleukin-2.
Schwartz RN, Stover L, Dutcher JP.
Schwartz RN, et al.
Oncology (Williston Park). 2002 Nov;16(11 Suppl 13):11-20.
Oncology (Williston Park). 2002.
PMID: 12469935
Free article.
Review.
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IL-2Rα-biased agonist enhances antitumor immunity by invigorating tumor-infiltrating CD25+ CD8+ T cells.
Wu W, Chia T, Lu J, Li X, Guan J, Li Y, Fu F, Zhou S, Feng Y, Deng J, Zou J, Sun J, Yao Y, Ling X, Wu Z, Zhang Y, Xu J, Wang F, Liang X, Wu M, Liu H, Chen B, He K.
Wu W, et al.
Nat Cancer. 2023 Sep;4(9):1309-1325. doi: 10.1038/s43018-023-00612-0. Epub 2023 Aug 7.
Nat Cancer. 2023.
PMID: 37550516
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