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. 2019 Mar 15;15(3):383-392.
doi: 10.5664/jcsm.7658.

Eating Late Negatively Affects Sleep Pattern and Apnea Severity in Individuals With Sleep Apnea

Tássia do Vale Cardoso Lopes  1 , Matheus Eduardo Borba  1 , Raíssa do Vale Cardoso Lopes  2 , Regina Mara Fisberg  2 , Samantha Lemos Paim  1 , Vinicius Vasconcelos Teodoro  1 , Ioná Zalcman Zimberg  3 , Cibele Aparecida Crispim  1
Affiliations

Eating Late Negatively Affects Sleep Pattern and Apnea Severity in Individuals With Sleep Apnea

Tássia do Vale Cardoso Lopes et al. J Clin Sleep Med. .

Abstract

Study objectives: This study aimed to analyze the association between habitual meal timing and sleep parameters, as well as habitual meal timing and apnea severity in individuals with obstructive sleep apnea (OSA).

Methods: Patients in whom mild to severe OSA was diagnosed were included in the study (n = 296). Sleep parameters were analyzed by polysomnography. Dietary pattern was obtained by a food frequency questionnaire and meal timing of the participants. Individuals with OSA were categorized by meal timing (early, late, and skippers).

Results: Dinner timing was associated with sleep latency (β = 0.130, P = .022), apnea-hypopnea index (AHI) (β = 1.284, P = .033) and poor sleep quality (β = 1.140, P = .015). Breakfast timing was associated with wake after sleep onset (WASO) (β = 3.567, P = .003), stage N1 sleep (β = 0.130, P < .001), and stage R sleep (β = -1.189, P = .001). Lunch timing also was associated with stage N1 sleep (β = 0.095, P = .025), sleep latency (β = 0.293, P = .001), and daytime sleepiness (β = 1.267, P = .009). Compared to early eaters, late eaters presented lower duration of stage R sleep and greater values of sleep latency, WASO, stage N1 sleep, and AHI, in addition to increased risk of poor sleep quality and daytime sleepiness (P < .005).

Conclusions: Late meal timing was associated with worse sleep pattern and quality and apnea severity than early meal timing. Despite some of these results having limited clinical significance, they can lead to a better understanding about how meal timing affects OSA and sleep parameters.

Keywords: OSA; REM sleep; eating duration; meal timing; nutrition; slow wave sleep.

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Figures

Figure 1
Figure 1. Study sample flow chart.
AHI = apnea-hypopnea index, OSA = obstructive sleep apnea, PSG = polysomnography.
See this image and copyright information in PMC

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References

    1. Punjabi NM. The epidemiology of adult obstructive sleep apnea. Proc Am Thorac Soc. 2008;5(2):136–143. - PMC - PubMed
    1. Young T, Palta M, Dempsey J, et al. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993;328(17):1230–1235. - PubMed
    1. Epstein LJ, Kristo D, Strollo PJ, Jr, et al. Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med. 2009;5(3):263–276. - PMC - PubMed
    1. Fernandes JFR, Araújo LS, Kaiser SE, Sanjuliani AF, Klein MRST. The effects of moderate energy restriction on apnoea severity and CVD risk factors in obese patients with obstructive sleep apnoea. Br J Nutr. 2015;114(12):2022–2031. - PubMed
    1. Gilardini L, Lombardi C, Redaelli G, et al. Glucose tolerance and weight loss in obese women with obstructive sleep apnea. PLOS One. 2013;8(4):e61382. - PMC - PubMed

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