Anti-inflammatory effects of phytochemicals from fruits, vegetables, and food legumes: A review
- PMID: 28605204
- DOI: 10.1080/10408398.2016.1251390
Anti-inflammatory effects of phytochemicals from fruits, vegetables, and food legumes: A review
Abstract
Inflammation is the first biological response of the immune system to infection, injury or irritation. Evidence suggests that the anti-inflammatory effect is mediated through the regulation of various inflammatory cytokines, such as nitric oxide, interleukins, tumor necrosis factor alpha-α, interferon gamma-γ as well as noncytokine mediator, prostaglandin E2. Fruits, vegetables, and food legumes contain high levels of phytochemicals that show anti-inflammatory effect, but their mechanisms of actions have not been completely identified. The aim of this paper was to summarize the recent investigations and findings regarding in vitro and animal model studies on the anti-inflammatory effects of fruits, vegetables, and food legumes. Specific cytokines released for specific type of physiological event might shed some light on the specific use of each source of phytochemicals that can benefit to counter the inflammatory response. As natural modulators of proinflammatory gene expressions, phytochemical from fruits, vegetables, and food legumes could be incorporated into novel bioactive anti-inflammatory formulations of various nutraceuticals and pharmaceuticals. Finally, these phytochemicals are discussed as the natural promotion strategy for the improvement of human health status. The phenolics and triterpenoids in fruits and vegetables showed higher anti-inflammatory activity than other compounds. In food legumes, lectins and peptides had anti-inflammatory activity in most cases. However, there are lack of human study data on the anti-inflammatory activity of phytochemicals from fruits, vegetables, and food legumes.
Keywords: Fruits and vegetables; animal model; anti-inflammatory property; food legumes; phytochemicals.
Similar articles
-
Bioactive Phytochemicals and Functional Food Ingredients in Fruits and Vegetables.Int J Mol Sci. 2020 May 6;21(9):3278. doi: 10.3390/ijms21093278. Int J Mol Sci. 2020. PMID: 32384609 Free PMC article.
-
Bioactive potential of fruit and vegetable wastes.Adv Food Nutr Res. 2020;91:157-225. doi: 10.1016/bs.afnr.2019.07.001. Epub 2019 Aug 1. Adv Food Nutr Res. 2020. PMID: 32035596 Review.
-
[Study on Effects and Mechanisms of Phytochemicals in Vegetables and Fruits in Preventing and Treating Lung Cancer].Zhongguo Fei Ai Za Zhi. 2017 Dec 20;20(12):841-846. doi: 10.3779/j.issn.1009-3419.2017.12.08. Zhongguo Fei Ai Za Zhi. 2017. PMID: 29277184 Free PMC article. Review. Chinese.
-
Interactions between phytochemicals from fruits and vegetables: Effects on bioactivities and bioavailability.Crit Rev Food Sci Nutr. 2018 May 24;58(8):1310-1329. doi: 10.1080/10408398.2016.1254595. Epub 2017 Jul 21. Crit Rev Food Sci Nutr. 2018. PMID: 27880063 Review.
-
Dietary bioactive compounds and their health implications.J Food Sci. 2013 Jun;78 Suppl 1:A18-25. doi: 10.1111/1750-3841.12101. J Food Sci. 2013. PMID: 23789932 Review.
Cited by
-
Standard and New Echocardio Techniques, Such as Global Longitudinal Strain, to Monitor the Impact of Diets on Cardiovascular Diseases and Heart Function.Nutrients. 2024 May 13;16(10):1471. doi: 10.3390/nu16101471. Nutrients. 2024. PMID: 38794710 Free PMC article. Review.
-
Paucatalinone A from Paulownia Catalpifolia Gong Tong Elicits mitochondrial-mediated cancer cell death to combat osteosarcoma.Front Pharmacol. 2024 Mar 25;15:1367316. doi: 10.3389/fphar.2024.1367316. eCollection 2024. Front Pharmacol. 2024. PMID: 38590635 Free PMC article.
-
Mediation Role of Recreational Physical Activity in the Relationship between the Dietary Intake of Live Microbes and the Systemic Immune-Inflammation Index: A Real-World Cross-Sectional Study.Nutrients. 2024 Mar 8;16(6):777. doi: 10.3390/nu16060777. Nutrients. 2024. PMID: 38542688 Free PMC article.
-
The predictive role of the dietary phytochemical index in relation to the clinical and psychological traits of migraine headaches.Sci Rep. 2024 Mar 22;14(1):6886. doi: 10.1038/s41598-024-57536-7. Sci Rep. 2024. PMID: 38519585 Free PMC article.
-
Phytochemicals and Their Usefulness in the Maintenance of Health.Plants (Basel). 2024 Feb 15;13(4):523. doi: 10.3390/plants13040523. Plants (Basel). 2024. PMID: 38498532 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials