The first person who comes to mind is Albert Camus who won the 1957 Nobel Prize for literature, and authored many writings that contributed to the ideas in the philosophy known as absurdism.
"...refers to the conflict between the human tendency to seek inherent value and meaning in life, and the human inability to find these with any certainty. The universe and the human mind do not each separately cause the Absurd; rather, the Absurd arises by the contradictory nature of the two existing simultaneously."
"In absurdist philosophy, the Absurd arises out of the fundamental disharmony between the individual's search for meaning and the meaninglessness of the universe. In absurdist philosophy, there are also two certainties that permeate human existence. The first is that humans are constantly striving towards the acquisition or identification with meaning and significance. It seems to be an inherent thing in human nature that urges the individual to define meaning in their lives. The second certainty is that the universe's silence and indifference to human life give the individual no assurance of any such meaning, leading to an existential dread within themselves. According to Camus, when the desire to find meaning and the lack of meaning collide, this is when the absurd is highlighted. The question then brought up becomes whether we should resign ourselves to this despair."
Many people may interpret these ideas as "a life without meaning is a life not worth living", and ultimately, the question is if we should consider suicide? Similar to the Shakespearian phrase "to be or not to be, that is the question" that we've all heard.
Camus understands this predicament and tackles this problem, and he comes to the conclusion that suicide is of little use, as there can be no more meaning in death than in life, and so the question of what makes life worth living arises.