This defect would be called "tombstone" , when a part mounted on its side or it stands up. Generally it is an indicator of quality of manufacture, but on certain applications the orientation may matter electrically or have poor contact.
MLCC generally mounted automatically from a tape and reel in the orientation that is most solderable. A suction nozzle grabs the part and puts it down on the board, the tape and reel technology is designed to have the part in the correct orientation for the automatic equipment.
Occasionally the component is rotated within the tape and reel , a packaging error, this may result in a poorly mounted part and is caught during inspection
For hand soldering, it is generally pretty easy to tell when side is "down" on the capacitor pancake , but with small parts like 0402 or 0603 it is common to tombstone the part when hand soldering for novices. Usually this is only a mechanical concern, but if you believe that there is an electrical need it only reinforces the interpretation of this as a defect.
Very occasionally the part is "square " (usually high density small sized caps), generally the manufacturer does not indicate the preferred axis and it would be considered over constraint for you to prefer an axis, likely for this kind of sensitive application there are specialty caps with asymmetry to have a fixed orientation. (Like a three/four lead feedthrough capacitor)