Depends on the application, there are two problems that affect electrical signals.
1) Resistance - Gold will have lower resistance and better soldering properties.
2) Seebeck effects - PCB solder junctions turn into small thermocouples which can make uV's of voltage offset. These offsets are depended on the temperature and the metals involved. Metals must be similar to avoid the seebeck effect. I don't know if this would be worse for gold but its something to be aware of. These affects would be around DC in frequency and would not affect faster systems.
http://circuitcellar.com/cc-blog/the-basics-of-thermocouples/
![enter image description here](https://cdn.statically.io/img/i.sstatic.net/CInqG.jpg)
If your looking to lower noise, changing the PCB metal is probably not the best place to be looking for noise reduction for analog circuits.