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What is the future of microbial expression systems? 🦠 Microbial expression systems are widely used to manufacture diagnostic and therapeutic proteins. However, the commercialization success rate for new drug developments is less than 3%, partly due to high development and manufacturing costs, long turnaround times, and challenging product safety profiles. 💸 CDMOs, including KBI, are jumping in to update microbial expression systems to surpass the modest yields of traditional E. coli models. KBI Biopharma has developed PUREcoli, a microbial expression system incorporating over 1,000 gene edits to enhance protein production. 📈 Learn more about it in our latest article! ⬇️ https://lnkd.in/d-KT-xbg #biotechinnovation #proteinproduction #therapeuticproteins #CDMOs #drugdevelopment #biomanufacturing #biotechresearch #biotechindustry

A new megadeal in the biotech industry?💸 The German biotech CatalYm GmbH just bagged $150 million in its series D funding round. The company is developing visugromab, a monoclonal antibody targeting the growth differentiation factor-15 (GDF-15) to tackle cancer therapy resistance. ❌ The results from phase 1/2  clinical trials are extremely promising and seem to have prompted the interest of new American investors in addition to the company’s historic backers. Visugromab is the only therapy targeting the GDF-15 and this investment is set to support the candidate's development. 💊 Find out more in our article! ⬇️ https://lnkd.in/d5-CWyZJ #biotechmegadeal #cancertherapy #biotechfunding #cancerresearch #pharmainvestments #biotechinnovation #medicalresearch #biotechindustry Phil L'Huillier

Did you know that Elephant endotheliotropic herpesvirus (EEHV) is the number one killer for Asian elephant calves living under managed care in North America and Europe, with a mortality rate of up to 85%? 🦠🐘 But there is now newfound hope in fighting against EEHV, as Houston Zoo recently announced that one of its elephants, named Tess, received the first-ever mRNA vaccination against the virus. 💉 Read our latest article to find out more about this vaccine and how mRNA vaccines in general could tackle other viruses afflicting animals! 👇️ https://lnkd.in/dMr8-NKM #EEHV #elephanthealth #wildlifeconservation #asianelephants #mRNAVaccine #animalhealth #veterinarymedicine #wildlifeprotection #innovativevaccines Baylor College of Medicine

Is Canada the place to study biotech? 🧑🎓 It certainly is! While U.S. universities still hold the first spots in biotechnology rankings, Canadian universities are well represented. It could also be a strategic choice to start your career with one of the many internship opportunities offered by Canadian universities. 💼 Indeed, it is expected that Canada is going to face shortages with an increase in vacancies in the biotech industry in the coming years, so Canadian companies might want you to stay after you graduate. 🤝 Discover five universities to study biotech in Canada below! ⬇️ https://lnkd.in/dktSMY5U #studybiotech #biotechcareers #careeropportunities #biotechindustry #biotechresearch #biotechjobs #STEMeducation #careerinbiotech #biotechgrowth McGill University | University of Alberta | The University of British Columbia | University of Toronto | University of Waterloo | BIOTECanada | Life Sciences Ontario | CQIB, Quebec Life Sciences Incubator & Accelerator | Genome Canada | BioAlberta | Life Sciences BC | BioTalent Canada | adMare BioInnovations

How are biotechs raising the bar for fatal liver disease treatments? 🧬 Acute on-chronic liver failure is a major healthcare issue with high unmet needs for patients, and a massive burden for healthcare systems. 🩺 French biopharma Genfit aims to take on rare, life-threatening liver diseases with a range of therapeutic targets. 🎯 💬 Labiotech spoke to GENFIT’s CSO Dean Hum about what treatments are on the way to treat the debilitating condition. 💊 🎧 Tune into the latest episode of the Beyond Biotech Podcast to find out about novel therapies addressing liver disease! 👇 https://lnkd.in/d59ENPAK #BeyondBiotechPodcast #liverdisease #biotechinnovation #healthcaresolutions #rarediseases #medicalresearch

💰 Biotech's Top Investments This Week! 🚀 🇺🇸 🇬🇧 Beacon Therapeutics | $170 million series B | gene therapies | phase 2/3 in X-linked retinitis pigmentosa 🇬🇧 Myricx Bio | £90 million ($114 million) series A | antibody drug conjugates | preclinical in cancer 🇩🇪 SciRhom | €63 million ($68.19 million) series A | antibody therapies | preclinical in autoimmune diseases 🇸🇪 SmartCella Holding AB | €50 million ($54.1 million) financing | drug delivery 🇺🇸 Trevena, Inc. | $2 million financing | central nervous system disorder therapies | phase 1 in diabetic neuropathic pain and epilepsy Subscribe to our newsletter for more fundraising updates! 🔗 https://lnkd.in/dsgz62YY #fundraising #funding #biotech #venturecapital #fundinground #biotechstartup #seriesa #seriesb #seriesc #investors #IPO #seedfunding

Is India going to replace China in the CDMO space? 👀 Two months ago, we discussed the WuXi AppTec controversy. To summarize after allegations that the Chinese CDMO had transferred U.S. companies’ information to the Chinese government, the American government responded with a bill, the BIOSECURE Act. This bill prevents U.S. biotechs from contracting with “biotechnology companies of concern”, including WuXi. ❌ While the act isn’t applicable yet, it seems that the arm is already done and the transition toward other CDMOs will progressively happen. WuXi is leaving an important gap in the area, and Indian CDMOs are more than ready to fill its shoes. ✅ Find out more in our latest article! ⬇️ https://lnkd.in/dAypkuik #CDMO #biotechindustry #biotechregulations #pharmamanufacturing #globalbiotech #pharmatrends Manni Kantipudi | Aragen Life Sciences | Alex Del Priore | Syngene International Limited | Himanshu Gadgil | Enzene Biosciences Ltd

Do you know of these bioinformatics companies making waves in the biopharma industry? 🌊 Bioinformatics is a field of science that integrates computer technology to analyze biological data to boost healthcare research. 🖥️ The bioinformatics industry has a market value of $16.3 billion at present, and is forecasted to reach nearly $24 billion in five years. 📈 Most biotechs rely on bioinformatics in drug discovery to improve their chances of viable candidates making it to the clinic. 🏥 Check out our latest article on five bioinformatics companies making a difference in the biopharma industry in 2024! 👇 https://lnkd.in/deQ7pvJY #bioinformatics #biopharma #healthcareresearch #drugdiscovery #biotechinnovation #BiotechIndustry #healthcaretech #scientificadvances Synthace | Verge Genomics | VeriSIM Life | Recursion | Twist Bioscience | Illumina | QIAGEN | Thermo Fisher Scientific

Discover Bridge RNA: A new gene editing technique to rival CRISPR.

What are the major treatments out there for skeletal dysplasia? 🦴 Skeletal dysplasias are a group of genetic disorders that disrupt bone growth. They affect around one in 5000 babies. 👶 As treatments are intended to alleviate painful symptoms, BioMarin Pharmaceutical Inc. and BridgeBio’s drugs are head-to-head in the clinic, but could one have a slight edge over the other? 🏥 Other drugs being developed include Ascendis Pharma’s Transcon CNP and Tyra Biosciences’ preclinical drug. 💊 Read our latest article to find out about recent therapeutic research in skeletal dysplasia! 👇 https://lnkd.in/dHSaSRER #skeletaldysplasia #bonedisorders #geneticdisorders #pediatrichealth #drugdevelopment #clinicaltrials #medicalresearch #healthcareinnovation