In MySQL Workbench, one can use the keyboard shortcut Ctrl + ENTER to execute the statement at cursor (delineated with semi colons).
Is there a similar shortcut in pgAdmin?
For SQL queries that span on only one line, I use a voice command in Dragon NaturallySpeaking:
Sub Main
SendKeys "{End}"
Wait(0.3)
SendKeys "+{Home}"
Wait(0.3)
SendKeys "{F5}"
End Sub
but I don't have any solution for SQL queries that span although more than one line.