All Questions
Tagged with chromatography synthesis
6
questions
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39
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Need Suggestion for Picking the Right Solvent for Column Chromatography
I've completed my reactions, and based on the stoichiometry and TLC analysis, I think my mixture should contain 3-4 compounds:
Ethyl gallate (my product)
Gallic acid (the reagent/starting material)
...
- 155
5
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3
answers
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Why will changing the solvent crack the column for column chromatography?
When we perform column chromatography with silica to purify the reaction crude product, we sometimes need to change the solvent system to better extract our target product.
For example, changing from ...
- 469
2
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Mixture is eluted too early from alumina in flash column chromatography
I have recently tried to purify my reaction mixture by column chromatography. Because my reaction mixture had poor resolution in silica-based TLC, I used neutral alumina-based TLC plate. After I ...
- 1,101
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Monitoring amino acid esterification
I am trying to monitor the esterification of a non UV active amino acid.I used thionyl chloride and Methanol as reagents.
As amino group is unprotected, Ninhydrin should give positive result for both ...
- 157
1
vote
1
answer
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Sephadex and purification of products [closed]
Sephadex is useful for the separation and purification of many natural products.
Is it also useful for the separation and purification of artificial chemicals (in organic synthesis ) or not and why ?
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10
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2
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How to separate two diastereomeric amines?
I am developing a method to synthesize amines using organometallic catalysts and my reaction yield these two diastereomeric amines ($\ce{R2N}$ is, in this case, a morpholine group).
With both being ...
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