Timeline for Reduction of benzylic alcohol and halide using H2 and Pd
Current License: CC BY-SA 4.0
4 events
| when toggle format | what | by | license | comment | |
|---|---|---|---|---|---|
| Nov 3, 2023 at 7:44 | comment | added | Mathew Mahindaratne | This recent article explains Zolpidem synthesis, which does not use $\ce{H2/Pd/BaSO4}$ after $\ce{PBr}$ reaction with allyl $\ce{OH}$ group as described in your methamphetamine synthesis route. There might be a mistake somewhere. | |
| Oct 31, 2023 at 21:03 | comment | added | user55119 | "Unusual" is a function of experience. | |
| Oct 31, 2023 at 11:07 | comment | added | Waylander | Hydrogenation is a standard method of removing benzyl ether protecting groups so there is ample precedent of cleaving O-Bn bonds whether ethers or alcohols. The stability of both the benzyl cation and radical facilitate this. | |
| Oct 31, 2023 at 1:58 | history | asked | Krang Lee | CC BY-SA 4.0 |