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    $\begingroup$ Are you asking for compound with smallest specific rotation? $\endgroup$ Commented Aug 8, 2020 at 6:33
  • $\begingroup$ Edited it... I wanted to ask something else $\endgroup$
    – user97495
    Commented Aug 8, 2020 at 6:34
  • $\begingroup$ It seems you're asking if "a molecule with chiral centres can have zero optical activity?". But, I'm not sure. $\endgroup$ Commented Aug 8, 2020 at 7:54
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    $\begingroup$ I very much doubt that there is a compound with exactly zero activity. Meso compounds are achiral (by definition) even though they contain stereo centers. $\endgroup$ Commented Aug 8, 2020 at 8:09
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    $\begingroup$ Do you mean allenes? they do have a stereocenter. $\endgroup$ Commented Aug 8, 2020 at 14:55