It is possible for an IRB to make a determination that your research, though it involves humans, does not rise to the level of human use that would require a whole protocol. I've gone down this road when trying to do 'experiments' that involve students using a web interface and having their activities recorded. It takes a few months and costs several hundred dollars, but it's probably the best case scenario for you.

That said, I do not know if you will be able to get such an exemption when you are drawing, storing and processing blood. Regardless of whose blood it is and whether they gave consent, there are legitimate concerns about infection. In this case, you may need to hire a group that does this kind of work and already has approved protocols in place.

It is possible for an IRB to make a determination that your research, though it involves humans, does not rise to the level of human use that would require a whole protocol. I've gone down this road when trying to do 'experiments' that involve students using a web interface and having their activities recorded. It takes a few months and costs several hundred dollars, but it's probably the best case scenario for you.

That said, I do not know if you will be able to get such an exemption when you are drawing, storing and processing blood. Regardless of whose blood it is and whether they gave consent, there are legitimate concerns about infection. In this case, you may need to hire a group that does this kind of work and already has approved protocols in place (or find an extant dataset from such a group that you can use).