You noted in the comments that you're using PowerPro. I am certain this is the cause of your troubles (and you confirmed this through your comments).
The PowerPro website notes that there is a version 4.9 available. This could possibly help with your issues. It may be worth a try.
In my personal opinion, the website of PowerPro does not look like it (or the software itself) is still well maintained. I would strongly advise you to look into alternative software.
Alternatives
Related: Multiple Monitor Software for Windows 7Multiple Monitor Software for Windows 7
Without knowing exactly what PowerPro provides to you, possibly a software like UltraMon (UltraMon costs US$39.95) is what you need.
Besides 3rd-party software. You already noted that you know about hotkeys in Windows 7 like Win+Shift+Left Arrow. In my opinion, a lot of valuable features regarding multi-monitor support were added in Windows 7 (like these hotkeys).