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    As per Homebrew's info, you should also use the --devel flag to build the experimental 64-bit build. The above won't work with a 64-bit python binary. (brew info wxmac says: "wxWidgets 2.8.x builds 32-bit only, so you probably won't be able to use it for other Homebrew-installed software. You can try to build with --devel to get the wxWidgets 2.9.x (unstable) for 64-bit and cocoa support.")
    – mbauman
    Commented May 18, 2012 at 20:48
  • I wish I could upvote you twice, sir.
    – Chris W.
    Commented Jun 13, 2012 at 21:06