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    Are you sure about your defrag comment? I recently defragged an NTFS file system that was very well used, almost full and had not been defragged in many years and noticed a huge performance improvement. Perhaps the "no difference" comment applies to the most common cases where a disk is generally underutilised?
    – luapyad
    Commented Aug 23, 2009 at 4:29
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    Defragmentation will run once a week on schedule anyway but yes, obsessive-compulsive defragmenting won't be of much use. If anything one only wastes time. Also, if you don't fill your disk further than like 75 percent it's unlikely fragmentation ever causes a performance problem.
    – Joey
    Commented Aug 24, 2009 at 14:53
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    WRT defrag, it depends. I used to daily work in an app that depended upon two files, one ~65MB in size and another ~2GB in size. When that app became "really slow", I went and ran a defrag analysis and discovered that, usually, one/both of those files were ~85% fragmented. After running defrag, the app sped up significantly.
    – J. Polfer
    Commented Aug 24, 2009 at 15:01
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    "Due to the way Windows handles files, it will in inevitably get slow over time." -> Do you have any reference for that? I know NTFS uses a MFT structure, but I never heard that this will necessarily always cause Windows to become slower.
    – sleske
    Commented Dec 9, 2010 at 21:58
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    I know this is old, but does anyone have reference to the "inevitable" slowing down of Windows due to MFT structure (with the only cure being a reformat)? I don't understand how it would only be a "one way street", with the only solution being a complete wipe and reinstall. It was my understanding that the days of "annual" Windows reformats to keep things snappy went away with the XP-era. Commented Jul 4, 2013 at 8:44