Microsoft's Windows To Go is notno longer available in Windows 10, version 2004 and later. Now, there are some unofficial software, such as iSumsoft SYSOnUSB. They can help install portable Windows 7/8/10/11 OS on an external hard drive or USB flash drive. Then, you can boot and run the Windows directly from the external drive without having to install it again.
- Connect the external hard drive to the software.
- Add the Windows ISO file to the software.
- Select the Windows version you want to install on the external drive.
- Start installing Windows on the external drive.
In this way, you can install a fresh Windows OS on your external hard drive. When you first boot from this drive, it will require you to take a few minutes to complete the Windows initialization setup to get to the Windows desktop, just like when you turn on a brand-new computer for the first time.