Quoted: I have received a few questions about this method - no it will not disable mice, or keyboards. It only disables storage devices attached to the USB port. This includes hard drives, flash drives, and any other type of USB storage device. And yes, if the user has administrator access they can reverse the changes.
How it operates is simple, we set a registry key that tells the UsbStor driver not to load on boot:
HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\UsbStor
Start = 4 (Disabled) - Don’t start the driver on boot
Start = 3 (Enabled) - Start the driver on boot
