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    This just disables Real-Time Protection it does not actually disable Windows Defender, which the existing answer, does actually.
    – Ramhound
    Commented Feb 7, 2016 at 4:27
  • If you have Windows 10 Pro, you can do this via gpedit.msc. Commented Nov 24, 2020 at 10:39
  • Very helpful to those who came here looking to disable antivirus only
    – Zimba
    Commented Mar 25, 2021 at 1:07
  • I don't think this answer is correct any more; the answer below is correct. Commented Mar 29, 2021 at 6:09