Human nutrition, the gut microbiome and the immune system
- PMID: 21677749
- PMCID: PMC3298082
- DOI: 10.1038/nature10213
Human nutrition, the gut microbiome and the immune system
Abstract
Marked changes in socio-economic status, cultural traditions, population growth and agriculture are affecting diets worldwide. Understanding how our diet and nutritional status influence the composition and dynamic operations of our gut microbial communities, and the innate and adaptive arms of our immune system, represents an area of scientific need, opportunity and challenge. The insights gleaned should help to address several pressing global health problems.
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References
-
- Whitacre PT, Fagen AP, Husbands JL, Sharples FE. Implementing the New Biology: Decadal Challenges Linking Food, Energy, and the Environment. National Research Council of The National Academies of Science; Washington, D.C.: 2010.
-
- Turnbaugh PJ, et al. The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci Transl Med. 2009;1:6ra14. This report highlights the utility of gnotobiotic mice harboring a transplanted human gut microbiome in studying the dynamic interplay between diet and the microbial community. - PMC - PubMed
-
- Bryce J, Boschi-Pinto C, Shibuya K, Black RE. WHO estimates of the causes of death in children. Lancet. 2005;365:1147–1152. - PubMed
-
- Bhutta ZA, et al. What works? Interventions for maternal and child undernutrition and survival. Lancet. 2008;371:417–440. - PubMed
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