Initial results of 3-dimensional 1H-magnetic resonance spectroscopic imaging in the localization of prostate cancer at 3 Tesla: should we use an endorectal coil?
- PMID: 21217527
- DOI: 10.1097/RLI.0b013e3182007503
Initial results of 3-dimensional 1H-magnetic resonance spectroscopic imaging in the localization of prostate cancer at 3 Tesla: should we use an endorectal coil?
Abstract
Purpose: The purpose of this study was to compare the diagnostic performance of 3 Tesla, 3-dimensional (3D) magnetic resonance spectroscopic imaging (MRSI) in the localization of prostate cancer (PCa) with and without the use of an endorectal coil (ERC).
Materials and methods: Our prospective study was approved by the institutional review board, and written informed consent was obtained from all patients. Between October 2004 and January 2006, 18 patients with histologically proven PCa on biopsy and scheduled for radical prostatectomy were included and underwent 3D-MRSI with and without an ERC. The prostate was divided into 14 regions of interest (ROIs). Four readers independently rated (on a 5-point scale) their confidence that cancer was present in each of these ROIs. These findings were correlated with whole-mount prostatectomy specimens. Areas under the receiver-operating characteristic curve were determined. A difference with a P < 0.05 was considered significant.
Results: A total of 504 ROIs were rated for the presence and absence of PCa. Localization of PCa with MRSI with the use of an ERC had a significantly higher areas under the receiver-operating characteristic curve (0.68) than MRSI without the use of an ERC (0.63) (P = 0.015).
Conclusion: The use of an ERC in 3D MRSI in localizing PCa at 3 Tesla slightly but significantly increased the localization performance compared with not using an ERC.
Similar articles
-
Impact of an endorectal coil for 1H-magnetic resonance spectroscopy of the prostate at 3.0T in comparison to 1.5T: Do we need an endorectal coil?Eur J Radiol. 2016 Aug;85(8):1432-8. doi: 10.1016/j.ejrad.2016.05.019. Epub 2016 May 31. Eur J Radiol. 2016. PMID: 27423684
-
A decade in prostate cancer: from NMR to metabolomics.Nat Rev Urol. 2011 May 17;8(6):301-11. doi: 10.1038/nrurol.2011.53. Nat Rev Urol. 2011. PMID: 21587223 Review.
-
Discriminating cancer from noncancer tissue in the prostate by 3-dimensional proton magnetic resonance spectroscopic imaging: a prospective multicenter validation study.Invest Radiol. 2011 Jan;46(1):25-33. doi: 10.1097/rli.0b013e3181f54081. Invest Radiol. 2011. PMID: 21188832
-
Prostate cancer: body-array versus endorectal coil MR imaging at 3 T--comparison of image quality, localization, and staging performance.Radiology. 2007 Jul;244(1):184-95. doi: 10.1148/radiol.2441060425. Epub 2007 May 10. Radiology. 2007. PMID: 17495178
-
Diagnosis of prostate cancer in patients with an elevated prostate-specific antigen level: role of endorectal MRI and MR spectroscopic imaging.AJR Am J Roentgenol. 2007 Mar;188(3):812-6. doi: 10.2214/AJR.06.0165. AJR Am J Roentgenol. 2007. PMID: 17312072
Cited by
-
Developments in proton MR spectroscopic imaging of prostate cancer.MAGMA. 2022 Aug;35(4):645-665. doi: 10.1007/s10334-022-01011-9. Epub 2022 Apr 20. MAGMA. 2022. PMID: 35445307 Free PMC article. Review.
-
Impact of the use of an endorectal coil for 3 T prostate MRI on image quality and cancer detection rate.Sci Rep. 2017 Feb 1;7:40640. doi: 10.1038/srep40640. Sci Rep. 2017. PMID: 28145525 Free PMC article.
-
MR Spectroscopic Imaging of Peripheral Zone in Prostate Cancer Using a 3T MRI Scanner: Endorectal versus External Phased Array Coils.Magn Reson Insights. 2013 May 15;6:51-8. doi: 10.4137/MRI.S10861. eCollection 2013. Magn Reson Insights. 2013. PMID: 25114544 Free PMC article.
-
Functional and molecular imaging of localized and recurrent prostate cancer.Eur J Nucl Med Mol Imaging. 2013 Jul;40 Suppl 1(Suppl 1):S48-59. doi: 10.1007/s00259-013-2419-6. Epub 2013 May 7. Eur J Nucl Med Mol Imaging. 2013. PMID: 23649462 Free PMC article. Review.
-
Multiparametric MRI of prostate cancer: an update on state-of-the-art techniques and their performance in detecting and localizing prostate cancer.J Magn Reson Imaging. 2013 May;37(5):1035-54. doi: 10.1002/jmri.23860. J Magn Reson Imaging. 2013. PMID: 23606141 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical