Breast cancer screening results 5 years after introduction of digital mammography in a population-based screening program
- PMID: 19703851
- DOI: 10.1148/radiol.2532090225
Breast cancer screening results 5 years after introduction of digital mammography in a population-based screening program
Abstract
Purpose: To compare full-field digital mammography (FFDM) using computer-aided diagnosis (CAD) with screen-film mammography (SFM) in a population-based breast cancer screening program for initial and subsequent screening examinations.
Materials and methods: The study was approved by the regional medical ethics review board. Informed consent was not required. In a breast cancer screening facility, two of seven conventional mammography units were replaced with FFDM units. Digital mammograms were interpreted by using soft-copy reading with CAD. The same team of radiologists was involved in the double reading of FFDM and SFM images, with differences of opinion resolved in consensus. After 5 years, screening outcomes obtained with both modalities were compared for initial and subsequent screening examination findings.
Results: A total of 367,600 screening examinations were performed, of which 56,518 were digital. Breast cancer was detected in 1927 women (317 with FFDM). At initial screenings, the cancer detection rate was .77% with FFDM and .62% with SFM. At subsequent screenings, detection rates were .55% and .49%, respectively. Differences were not statistically significant. Recalls based on microcalcifications alone doubled with FFDM. A significant increase in the detection of ductal carcinoma in situ was found with FFDM (P < .01). The fraction of invasive cancers with microcalcifications as the only sign of malignancy increased significantly, from 8.1% to 15.8% (P < .001). Recall rates were significantly higher with FFDM in the initial round (4.4% vs 2.3%, P < .001) and in the subsequent round (1.7% vs 1.2%, P < .001).
Conclusion: With the FFDM-CAD combination, detection performance is at least as good as that with SFM. The detection of ductal carcinoma in situ and microcalcification clusters improved with FFDM using CAD, while the recall rate increased.
(c) RSNA, 2009.
Similar articles
-
Impact of full field digital mammography on the classification and mammographic characteristics of interval breast cancers.Eur J Radiol. 2015 Jun;84(6):1056-61. doi: 10.1016/j.ejrad.2015.03.007. Epub 2015 Mar 14. Eur J Radiol. 2015. PMID: 25816990 Review.
-
Full-field digital versus screen-film mammography: comparison within the UK breast screening program and systematic review of published data.Radiology. 2009 May;251(2):347-58. doi: 10.1148/radiol.2512081235. Radiology. 2009. PMID: 19401569 Review.
-
Randomized trial of screen-film versus full-field digital mammography with soft-copy reading in population-based screening program: follow-up and final results of Oslo II study.Radiology. 2007 Sep;244(3):708-17. doi: 10.1148/radiol.2443061478. Radiology. 2007. PMID: 17709826 Clinical Trial.
-
Follow-up and final results of the Oslo I Study comparing screen-film mammography and full-field digital mammography with soft-copy reading.Acta Radiol. 2005 Nov;46(7):679-89. doi: 10.1080/02841850500223547. Acta Radiol. 2005. PMID: 16372686
-
Screen-film mammography versus full-field digital mammography with soft-copy reading: randomized trial in a population-based screening program--the Oslo II Study.Radiology. 2004 Jul;232(1):197-204. doi: 10.1148/radiol.2321031624. Epub 2004 May 20. Radiology. 2004. PMID: 15155893 Clinical Trial.
Cited by
-
Tensor-Based Learning for Detecting Abnormalities on Digital Mammograms.Diagnostics (Basel). 2022 Oct 1;12(10):2389. doi: 10.3390/diagnostics12102389. Diagnostics (Basel). 2022. PMID: 36292078 Free PMC article.
-
Can a Computer-Aided Mass Diagnosis Model Based on Perceptive Features Learned From Quantitative Mammography Radiology Reports Improve Junior Radiologists' Diagnosis Performance? An Observer Study.Front Oncol. 2021 Dec 17;11:773389. doi: 10.3389/fonc.2021.773389. eCollection 2021. Front Oncol. 2021. PMID: 34976817 Free PMC article.
-
Patterns of treatment and outcome of ductal carcinoma in situ in the Netherlands.Breast Cancer Res Treat. 2021 May;187(1):245-254. doi: 10.1007/s10549-020-06055-w. Epub 2021 Jan 1. Breast Cancer Res Treat. 2021. PMID: 33385265 Free PMC article.
-
Effect of Different Types of Mammography Equipment on Screening Outcomes: A Report by the Alliance for Breast Cancer Screening in Korea.Korean J Radiol. 2019 Dec;20(12):1638-1645. doi: 10.3348/kjr.2019.0006. Korean J Radiol. 2019. PMID: 31854151 Free PMC article.
-
Comparison of Digital and Screen-Film Mammography for Breast-Cancer Screening: A Systematic Review and Meta-Analysis.J Breast Cancer. 2019 Jun;22(2):311-325. doi: 10.4048/jbc.2019.22.e24. J Breast Cancer. 2019. PMID: 31281732 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous