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. 2008 Mar;21(1-2):149-58.
doi: 10.1007/s10334-007-0101-3. Epub 2008 Jan 11.

MR venography of the human brain using susceptibility weighted imaging at very high field strength

Peter J Koopmans  1 , Rashindra Manniesing, Wiro J Niessen, Max A Viergever, Markus Barth
Affiliations

MR venography of the human brain using susceptibility weighted imaging at very high field strength

Peter J Koopmans et al. MAGMA. 2008 Mar.

Abstract

Objective: We investigate the implications of high magnetic field strength on MR venography based on susceptibility-weighted imaging (SWI) and estimate the optimum echo time to obtain maximum contrast between blood and brain tissue.

Materials and methods: We measured tissue contrast and T2* relaxation times at 7 T of gray matter, white matter, and venous blood in vivo.

Results: T2* relaxation times of gray matter, white matter, and venous blood in vivo yielded 32.9 +/- 2.3, 27.7 +/- 4.3, and 7.4 +/- 1.4 ms, respectively. Optimum TE was found to be 15 ms which is supported by theoretical considerations. Using this optimum TE, we acquired 3D high resolution datasets with a large volume coverage in a short measurement time that show very detailed microanatomical structures of the human brain such as intracortical veins and laminar cortical substructures.

Conclusions: By applying optimised vessel filters (vesselness filter and vessel enhancing diffusion) whole brain MR venograms can be obtained at 7 T with a significantly reduced measurement time compared to 3 T.

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