Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Apr;11(2):146-56.
doi: 10.1016/j.media.2006.11.003. Epub 2007 Jan 8.

Gray-scale and geometric registration of full-field digital and film-screen mammograms

Peter R Snoeren  1 , Nico Karssemeijer
Affiliations

Gray-scale and geometric registration of full-field digital and film-screen mammograms

Peter R Snoeren et al. Med Image Anal. 2007 Apr.

Abstract

During the transition from traditional film-screen (FS) mammography to full-field digital (FFD) mammography, images from both modalities are used in hospitals and in mammography screening centers, as comparison of mammograms from subsequent examinations of a client is an important part of the diagnostic procedure. A parametric method is presented to register a FS mammogram and a FFD mammogram of the same woman with respect to geometry and gray-scales. The main motivation for the study is to lessen irrelevant differences between mammograms due to acquisition. First, a technique like this might increase the radiologist's ability to detect relevant differences like abnormal growth in breast tissue that signal breast cancer. Second, applications may be found in subtraction radiology or in computer-aided detection of abnormalities in temporal mammograms. The proposed method is based on a parametric model of the most important aspects of acquisition, which relates the pixel values of two images. This encompasses (1) breast positioning; (2) breast compression; (3) exposure time; (4) incident radiation intensity; and (5a) film properties and digitization for FS mammograms, or (5b) detector response for FFD mammograms. The method does not require a priori knowledge about specific settings of acquisition; the parameters are estimated from the two mammograms themselves.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

  • A statistical approach for breast density segmentation.
    Oliver A, Lladó X, Pérez E, Pont J, Denton ER, Freixenet J, Martí J. Oliver A, et al. J Digit Imaging. 2010 Oct;23(5):527-37. doi: 10.1007/s10278-009-9217-5. Epub 2009 Jun 9. J Digit Imaging. 2010. PMID: 19506953 Free PMC article.